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Background: Patients with obstructive sleep apnea (OSA), related to their disease consequences and treatment modalities, are physically and mentally vulnerable during the outbreak. Objectives: To investigate the association between pandemic-related changes and positive airway pressure (PAP) adherence and sleep quality in OSA patients. Methods: This was a multi-center cross-sectional study, and the necessary data were collected prospectively. A total of 221 patients were included in the study, who were invited from four different centers from June 1 - December 1, 2020. Pittsburgh Sleep Quality Index (PSQI) was administered to evaluate sleep quality. Information on demographics positive airway pressure (PAP) device use, Coronavirus disease (COVID-19) a questionnaire collected related changes. Patients >18 years with a diagnosis of OSA and prescribed PAP treatment before the pandemic period were included in the study. Lack of cooperation with the questionnaires and incompliant with PAP treatment for longer than one year were the exclusion criteria. Results: Of the 221 participants, 79.2% were men. The mean apnea-hypopnea index was obtained at 40.8+or-24.3. A positive COVID-19 test was reported in nine cases, and three patients had hospitalization. During the pandemic, 102 (46.2%) subjects were retired, 26 (11.8%) lost their jobs, and 34 (15.3%) reported home office work or on-call or on leave. Poor sleep quality was found in 54 (24.4%) individuals. It was also reported that poor sleep quality was more common in those who reported mask use difficulty (38.7% vs. 18.9%;P=0.004) and increased or decreased PAP use (increased, decreased, no change in PAP use: 45.5%, 36.0%, 19.4%, respectively;P=0.01). The good sleep quality group had higher PAP use than the poor sleep quality group (6.2+or-1.5 vs. 5.3+or-2.4 night/week;P=0.002;6.2+or-1.5 vs. 5.5+or-2.2 hour/night;P=0.01). Conclusions: Pandemic period had several negative effects on sleep apnea patients regarding sleep quality and social lives which also influenced PAP adherence in OSA patients. Most patients did not change their regular PAP use attitudes during this period. Similar to the pre-COVID-19 disease period, PAP adherence and compliance positively influenced sleep quality;people who were "good sleepers" were the ones who were the "good PAP device users".
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Cold agglutinin disease(CAD) is an autoimmune disease that occurs against erythrocyte antigens. It is usually idiopathic, but some infections can also be a trigger. CAD becomes active in the peripheral circulation at lower temperatures more easily when exposed to cold, causing hemolysis or agglutination. In this article, the management of a coronary bypass case with CA formation in intraoperative period is presented. A 46-year-old diabetic and hypertensive male patient had COVID-19 2 months ago. Cardiopulmonary bypass(CPB) was initiated with adequate heparinization, and the patient was cooled to 32degreeC. It was noticed that there were clots in the cardioplegia delivery line(+1degreeC). Agglutinations were observed in the autologous blood of the patient whose ACT values were normal. After CPB, the operation was completed without any problems and the patient was discharged on the 5th day with recovery. A diagnosis of CAD was made with the results of peripheral smear and immunologic tests. Determination of antibody concentration and thermal amplitude in the preoperative period in patients with CAD is very important. While preparing such patients for surgery, heating of room, patient, fluids, planning of normothermic CPB, and using warm cardioplegia are required. The relationship between CAD and COVID has started to take place in the literature. The patient we presented had a COVID 2 months ago, cold agglutinin may have been induced by COVID or may have arisen idiopathic. Considering that many people may have had a COVID nowadays, care should be taken especially in the perioperative period of cardiac surgery.Copyright © Telif hakki 2022 Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi - Available online at www.gkdaybd.org.
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Cold agglutinin disease(CAD) is an autoimmune disease that occurs against erythrocyte antigens. It is usually idiopathic, but some infections can also be a trigger. CAD becomes active in the peripheral circulation at lower temperatures more easily when exposed to cold, causing hemolysis or agglutination. In this article, the management of a coronary bypass case with CA formation in intraoperative period is presented. A 46-year-old diabetic and hypertensive male patient had COVID-19 2 months ago. Cardiopulmonary bypass(CPB) was initiated with adequate heparinization, and the patient was cooled to 32degreeC. It was noticed that there were clots in the cardioplegia delivery line(+1degreeC). Agglutinations were observed in the autologous blood of the patient whose ACT values were normal. After CPB, the operation was completed without any problems and the patient was discharged on the 5th day with recovery. A diagnosis of CAD was made with the results of peripheral smear and immunologic tests. Determination of antibody concentration and thermal amplitude in the preoperative period in patients with CAD is very important. While preparing such patients for surgery, heating of room, patient, fluids, planning of normothermic CPB, and using warm cardioplegia are required. The relationship between CAD and COVID has started to take place in the literature. The patient we presented had a COVID 2 months ago, cold agglutinin may have been induced by COVID or may have arisen idiopathic. Considering that many people may have had a COVID nowadays, care should be taken especially in the perioperative period of cardiac surgery.Copyright © Telif hakki 2022 Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi - Available online at www.gkdaybd.org.
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Background: Ventilator associated events (VAE) algorithm is increasingly used for the surveillance of ventilator associated problems as an alternative tool of traditional ventilator associated pneumonia (VAP) definition for surveillance. COVID-19's impact on reliability of VAE for VAP is poorly defined. Aims and objectives: To compare the performance of traditional VAP criteria with VAE criteria to detect ventilator associated problems in intensive care unit (ICU) patients with COVID-19 pneumonia. Method(s): Patients who were intubated for more than 48 hours in COVID-19 ICU were included. COVID-19 was diagnosed with polymerase chain reaction. For traditional VAP surveillance definition, CDC PNEU/VAP criteria were used. For VAE definition, CDC/NHSN VAE algorithm was used. Both VAE and PNEU/VAP surveillance were conducted manually by two investigators who were blind to each other. NHSN VAE calculator version 8.1 was used to verify VAE. Result(s): Seventy-seven patients met inclusion criteria during the 1-year study period. Mean (+/- SD) age was 68.7 (+/-13), 67.5% were male, median Charlson comorbidity index score was 4 (IQR 3). Thirty-three patients were diagnosed as PNEU/VAP. VAE were detected in fifteen patients. Eleven patients met both VAP and VAE criteria. The VAP rate was 13.55 per 1000 ventilator days, VAE rate was 6.16 per 1000 ventilator days. Conclusion(s): CDC PNEU/VAP criteria detected higher rate of ventilator associated problems when compared with VAE in patients with COVID-19.
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Objective: The COVID-19 outbreak that has spread all around the world is still a threat for humankind. Epidemiological, clinical, laboratory, and radiological features of the disease are enlightened day by day. It was aimed to evaluate the characteristics of children and their parents with COVID-19 to aid in diagnosis and treatment. Material(s) and Method(s): A retrospective review of the medical records of pediatric patients and their parents who were confirmed as COVID-19 positive, between April 23, and May 28, 2020, was conducted. Result(s): A total of 93 children and 81 adults were evaluated in the present study. Asymptomatic and mild cases accounted for 63.5% of the children and 50% of the parents. Of the children, 3.2% had moderate illness, whereas this was 9.8% for the parents There was a statistically significant difference in terms of the severity of illness between the children and their parents (p =0.01). Although it had a milder clinical course in children, one child died. Increased levels of C-reactive protein (CRP) were observed in 8.6% of the children and 48.1% of the patients, and there was statistically significant difference in terms of CRP levels between the children and their parents (p =0.001). Conclusion(s): The clinical, laboratory, and radiological features of COVID-19 showed differences in the children and their parents. It should be kept in mind that COVID-19 can be fatal in children, although the course of the disease appears to be milder in children than in their parentsCopyright © 2023 Ankara Pediatric Hematology Oncology Training and Research Hospital. All rights reserved.
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Objective: This study aimed to assess fecal viral shedding in children who have been confirmed COVID-19 by real time polymerase chain reaction (RT-PCR). Material(s) and Method(s): We enrolled fifty inpatient children who have been confirmed COVID-19 during first wave of outbreak in our region. All of the patients have been twice confirmed by RT-PCR within nasopharyngeal swabs. Each case was evaluated with clinical data, laboratory tests and rectal swabs. The rectal swabs were obtained five days after nasopharyngeal positivity. The clinical data was recorded within two basic categories, including common symptoms or digestive symptoms. Detection of SARS-CoV-2 in rectal swabs was performed by RT-PCR method. Result(s): Fifteen patients (30%) had digestive symptoms. On the 5th day, 50 rectal swabs were studied with PCR-RT. Only one of them was positive (2%). The only patient who was positive for SARS-CoV-2 on rectal swab was a symptomatic threeand-a-half-year-old girl. The patient, who became asymptomatic in the follow-up, was retested with a nasopharyngeal swab one week later, the result was negative and she was discharged on the 10th day. The second rectal smear of the patient was negative. Conclusion(s): We found very low rate (2%) fecal viral shedding with rectal swab PCR among children who have been confirmed COVID-19 by nasopharyngeal swab PCR. We thought that this result was due to the mild clinical course of the patients who has been diagnosed with COVID-19 we followed up. However, fecal oral transmission might still matter in children. Copyright © 2022 Ankara Pediatric Hematology Oncology Training and Research Hospital. All rights reserved.
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Objective: Febrile convulsion is a common seizure type in children between 6 months and 6 years of age and is seen in 2%-5% of children.1 Coronavirus disease 2019 spread rapidly and became a pandemic. As coronavirus disease 2019 can be seen in epilepsy patients, the relationship between coronavirus disease 2019 and seizures is not clear yet.2 This study aimed to evaluate the characteristics of coronavirus disease 2019-positive patients with febrile convulsions and compare them with coronavirus disease 2019-negative patients with febrile convulsions regarding their clinical features.Methods: Forty patients were included in the study. In our country, diagnosing, monitoring, and treating coronavirus disease 2019 are performed according to the Turkish Ministry of Health coronavirus disease 2019 Scientific Committee guidelines.Results: Twelve of the patients were coronavirus disease 2019 positive, whereas 28 were coronavirus disease 2019 negative. While the rate of complex febrile convulsion was 50% in the coronavirus disease 2019-positive group, this ratio was 25% in the coronavirus disease 2019-negative patient group.Conclusions: Seizures occur in the presence of higher-grade fever in coronavirus disease 2019-positive cases. On the other hand, the probability of seizures to occur focally and recur during the same disease period might be higher. Male gender and maternal history of febrile convulsions may be the risk factors.
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The wide distribution of access points in Izmir allows the collected information to be employed in smart city algorithms. In this study, we analyze the information that has been made publicly available by Izmir Metropolitan Municipality. We first show that the data is reliable, then analyze it from the perspectives of holidays, seasonal trends, and the COVID-19 pandemic. The study also shows that the information can be used for crowd analysis and forecasting, using K-means and SARIMA algorithms, respectively. © 2022 IEEE.
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Background and Aim: In this study, the relationship of revascularization via percutaneous coronary intervention (PCI) with 1-month mortality in non-ST-elevation myocardial infarction (NSTEMI) patients with active COVID-19 infection, coronary angiography (CAG) and PCI application preferences of cardiologists to COVID-19 patients, and the infection rates of the personel working in the angio of the active COVID-19 patient will be investigated. Method(s): The study included 101 consecutive patients who were admitted to our clinic with the diagnosis of NSTEMI while they had active COVID-19 infection between 03/2020 and 02/2021. Patients were divided into two groups as those who were revascularized by PCI and those who were not. The angio records of the patients who underwent CAG but did not undergo PCI were re-evaluated by two cardiologists blinded to the study, and the patients who were deemed to need PCI by both cardiologists were determined. On the other hand, cardiologists, nurses and angio technicians who entered the procedure of patients who underwent CAG were identified from the hospital records and the results of those who gave the COVID-19 test within 14days after the procedure were recorded. Result(s): CAG was performed in 62.4% of the patients included in the study. The rates of performing CAG were significantly lower in patients in the severe-critical COVID-19 category. Only 46.0% of the patients who underwent CAG were revascularized with PCI. The 1-month mortality rate in our study was 24.8%. In the regression analysis, revascularization with PCI was associated with 1-month mortality, independent of age and COVID-19 category, while the absence of revascularization increased mortality by approximately 5times. When 34 patients who underwent CAG and did not undergo PCI were evaluated retrospectively, 5 (14.7%) patients were found to be suitable for PCI. A total of 48 personnel took part in 63CAG operations. 13 COVID-19 tests were performed by the personnel in charge within 14 days after the procedure, but none of the tests were positive. Conclusion(s): When compared to the studies in the literature in the similar period, it was seen that CAG was applied to patients at a higher rate. Despite this, most of the patients, especially in the advanced COVID-19 category, were deprived of this opportunity. In addition, although they did not have a large rate, it was observed that some of the patients who underwent CAG could be treated with PCI, but not. We think that the fear of prolonged contact time with a COVID-19 patient may play a role in this situation. In our study, it was determined that revascularization with PCI was associated with 1-month mortality regardless of age and COVID-19 category. On the other hand, no healthcare personnel were infected due to being in the process of the COVID-19 patient. Considering these two results together, we think that the approach to COVID-19 patients diagnosed with NSTEMI should not be different from other patients, provided that necessary precautions are taken. .
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Background. Sports events are considered activities carried out in a specific schedule to handle all kinds of sports competitions and activities, such as seminars, meetings, courses, panels, and camps, organized for sports purposes. Methods. In this study, we aimed to discuss sports events during the pandemic. In this context, the present study targeted the 16th NKolay Istanbul Half Marathon on April 4, 2021, and recruited the randomly selected 125 female (23.1%) and 417 male (76.9%) marathon runners in this event. We gathered the data using a demographic information format and a 14-item scale. Results. We sought answers to four hypotheses by employing a descriptive survey model. Initially, we carried out a pilot study with a sample of 30 people to explore the validity of the scale and replicated the validity study for the primary sample. We performed exploratory factor analysis with the varimax rotation method for the validity study and attempted to confirm the resultant factorial structure using confirmatory factor analysis. We utilized a T-test and one-way analysis of variance to investigate whether the subscales of the survey differed significantly by the participants' demographics. We ran statistical analyses on SPSS 20.0 at the 95% confidence interval. Conclusion. The findings confirmed our first two hypotheses. We were able to confirm the third hypothesis partially. Accordingly, the participants significantly differed in the race destination subscale by only income. Finally, our results rejected the fourth hypothesis. Overall, we may assert that COVID-19 is a prime concern for half marathon runners.
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Background & Objective: Tension-type headache (TTH) is the most common primary headache. TTH worsens quality of life and is related to various psychosocial factors. We aimed to examine the severity of headache (intensity, frequency, and duration), analgesic use, quality of life (QoL), and the impact of COVID pandemic-induced stress in TTH patients. Method(s): TTH cases seen at neurology outpatient clinics in 15 centers in Turkey were included in the study. A questionnaire incorporating sociodemographic and medical information, headache features, sleep quality, general quality of life, and impact of the pandemic event was administered to the subjects. Result(s): A total of 975 TTH patients were evaluated. Headache severity was higher in women as well as in patients with a history of COVID-19 contact. Women, those with chronic diseases, and cases with a COVID-19 contact history had worse perceptions of quality of life and were affected to a greater extent by the pandemic. The factors affecting the impact of the pandemic were female gender and difficulty in access to health services for headache. Co-existing chronic diseases and lost productive time due to headaches were negative determinants for both QoL and the impact of the pandemic. Conclusion(s): Our results show that the COVID pandemic severely worsened the headache burden, quality of life and mental health of TTH patients. These findings can guide us in the clinical approach to TTH cases. Copyright © 2022, ASEAN Neurological Association. All rights reserved.
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Study objective: The lockdown imposed on children due to the COVID-19 pandemic and their inability to attend school increased their exposure to indoor allergens by causing them to spend more time indoors. In this study, the aim was to reveal the effect of the pandemic and increased exposure to indoor aeroallergens on the symptom severity of school-age children with house dust mite-sensitized allergic rhinitis (AR). Patients and methods: Patients between the ages of 6-18-years old, who were followed-up with the diagnosis of perennial AR sensitized to only mites were questioned about their sinonasal symptoms. The Total Nasal Symptom Score (TNSS) questionnaire was performed. The clinical findings, drug usage, frequency of infections and attacks were evaluated and compared during COVID-19 lockdown and the same time frame in 2019. Results: Sixty-five patients had AR, and 33 patients (50.8%) had AR with asthma. TNSS of the patients improved during the pandemic (P < 0.001) and their medication scores decreased significantly (P < 0.001). The frequency of respiratory tract infections and asthma attacks decreased significantly (P < 0.001). In multivariate analysis, risk factors were evaluated for the 'group with worsening TNSS' and coal/wood burning was detected to be an independent risk factor (P = 0.006; OR = 10.09 (95% CI: 1.97-51.87)). Conclusion: Although the increased stay at home, it is surprising that nasal symptoms improved in our patients. This result suggests that whereas allergen sensitivity is responsible for the pathogenesis of AR, exposure to pollution and viral infections which are reduced by masking and social distance may also play an important role in the pathogenesis.
Introduction: Le confinement imposé aux enfants en raison de la pandémie de COVID-19, l'impossibilité pour les enfants d'aller à l'école; ont augmenté leur exposition aux allergènes intérieurs en les obligeant à passer plus de temps à l'intérieur. Dans cette étude, il visait à révéler l'effet de la période pandémique et de l'exposition accrue aux aéroallergènes intérieurs sur la sévérité des symptômes des enfants d'âge scolaire atteints de rhinite allergique (RA) sensibilisée aux acariens. Méthode: Patients âgés de 6 à 18 ans, qui ont été suivis avec le diagnostic de RA perannuelle avec seulement des acariens sensibilisés; ont été interrogés sur leurs symptômes naso-sinusiens. Le questionnaire Total Nasal Symptom Score (TNSS) a été réalisé. Leurs résultats cliniques, l'utilisation de médicaments, la fréquence des infections et des attaques ont été évalués et comparés pendant le verrouillage de COVID-19 et la même période de 2019. Résultats: Soixante-cinq patients avaient une RA et 33 patients (50,8 %) avaient une RA avec asthme. Le TNSS des patients pendant la période pandémique s'est amélioré (p < 0,001) et leurs scores de médication ont diminué de manière significative (p < 0,001). La fréquence des infections des voies respiratoires et des crises d'asthme a diminué significativement (p < 0,001). En analyse multivariée, les facteurs de risque ont été évalués pour le « groupe d'aggravation du TNSS ¼, la combustion de charbon/bois a été détectée comme étant un facteur de risque indépendant (p = 0,006 ; OR = 10,09 (IC95 % : 1,9751,87)). Conclusion: Malgré l'augmentation du séjour à domicile, il est surprenant que les symptômes nasaux de nos patients se soient améliorés. Ce résultat suggère que si la sensibilité aux allergènes est responsable de la pathogenèse de la RA, l'exposition à la pollution et aux infections virales qui sont réduites par le masque et la distance sociale peuvent également jouer un rôle important dans la pathogenèse.
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Purpose - The aim of the current study was to evaluate the effects of work-life balance (WLB) on the employee motivation (EM), job satisfaction (JS) and emloyee performance (EP) of academic staff at universities. Design/methodology/approach - In this regard, the authors collected 490 valid data from academic staff of major public and private universities in Kurdistan Region of Iraq. WLB was evaluated under three dimensions as work interference with personal life (WIPL), personal life interference with work (PLIW) and work personal life enhancement (WPLE). Findings - The results of the analyses showed that WIPL and PLIW negatively and significantly affected EM but did not have any significant impact on JS. WPLE affected both JS and EM significantly and positively. Lastly, JS did not have significant impact on EP while EM did. Research limitations/implications - As the research was conducted in Kurdistan Region of Iraq, it cannot be generalized to other countries and cultures. Practical implications - Besides, the study suggests theoretical and practical implication as it was a special study proposed during COVID 19 lock downs. Originality/value - There are very limited or no research works which attempt to study the pros and cons of WLB during such a catastrophic time, the study is useful for the university administrators and researchers in this field.
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Objective: This study aimed to investigate the psychogenic impact of coronavirus disease-2019 (COVID-19) and its association with myalgia-arthralgia in patients who are hospitalized with COVID-19. Materials and Methods: This study includes patients who were hospitalized with COVID-19 and whose diagnoses were confirmed by thoracic computed tomography findings and positive polymerase chain reaction test. Characteristics of pain were evaluated using the pain quality assessment scale (PQAS). Posttraumatic stress disorder (PTSD) was evaluated with the impact of event scale-revised (IES-R). Scoring over 33 was considered a cut-off point for “probable PTSD”. These patients were named PTSD (+). PTSD (+) and PTSD (-) groups were compared in terms of PQAS and laboratory parameters. Results: Of the participants, 70 (42.9%) were females and 93 (57.1%) were males. The mean IES-R score was 36.89±11.76. The prevalence of PTSD was 47.9% (n=78). The most common pain was back pain (n=52, 50.5%). Patients with myalgia-arthralgia had higher total IES-R score and subgroup scores (p=0.008, p=0.010, p=0.006, and p=0.012, respectively). The patient group with PTSD had higher PQAS score (p=0.001). Additionally, this group had lower leukocyte (p=0.002) and lymphocyte counts (p=0.010) and higher serum creatine kinase level (p=0.02). Conclusion: Approximately half of the patients who were hospitalized with COVID-19 had PTSD, with a higher incidence and severity of myalgia-arthralgia. Therefore, myalgia-arthralgia was associated with PTSD in patients who were hospitalized with COVID-19. © 2021 by Turkish Neurological Society Turkish Journal of Neurology published by Galenos Publishing House.
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OBJECTIVE: The primary goal of this study was to evaluate the association between olfactory dysfunction or taste impairment and disease severity and radiological findings in coronavirus disease-2019. The secondary goal was to assess the prevalence, severity and course of olfactory dysfunction or taste impairment in patients with coronavirus disease 2019. METHOD: This prospective observational cohort study evaluated patients hospitalised with coronavirus disease 2019 between April 1 and 1 May 2020. Olfactory dysfunction and taste impairment were evaluated by two questionnaires. Chest computed tomography findings and coronavirus disease-2019 severity were assessed. RESULTS: Among 133 patients, 23.3 per cent and 30.8 per cent experienced olfactory dysfunction and taste impairment, respectively, and 17.2 per cent experienced both. The mean age was 56.03 years, and 64.7 per cent were male and 35.3 per cent were female. No statistically significant association was found between olfactory dysfunction (p = 0.706) and taste impairment (p = 0.35) with either disease severity or chest computed tomography grading. CONCLUSION: Olfactory dysfunction or taste impairment does not have prognostic importance in patients with coronavirus disease 2019.
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COVID-19/complicaciones , Trastornos del Olfato/epidemiología , SARS-CoV-2 , Índice de Severidad de la Enfermedad , Trastornos del Gusto/epidemiología , Adulto , Anciano , COVID-19/diagnóstico por imagen , Femenino , Hospitalización/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Trastornos del Olfato/virología , Prevalencia , Pronóstico , Estudios Prospectivos , Trastornos del Gusto/virología , Tomografía Computarizada por Rayos XRESUMEN
Aim: To investigate the complaints and findings of COVID-19 infection in a paediatric age group. Material and Method: The study included 130 patients with COVID-19 infection confirmed with reverse-transcription polymerase chain reaction (RT-PCR) test positivity. The cases were evaluated in respect of demographic data, such as age and gender, and clinical findings, such as fever, weight, cough, shortness of breath, and history of infectious contact. Results: Evaluation was made of 130 COVID-19-positive paediatric patients, comprising 69 (53%) males and 61 (47%) females, of which 54% were asymptomatic and 5.4% had severe clinical findings requiring follow up in the Intensive Care Unit (ICU). Of the symptomatic patients, fever was determined in 30%, listlessness in 24%, cough in 10.8%, respiratory problems in 9.2%, diarrhea in 6.2%, abdominal pain in 6.2%, vomiting in 2.3%, joint pain in 2.3%, and convulsions developed in 1.5% who had no previous history of convulsions. Of the 7 patients who required intensive care, 2 had cerebral palsy, 1 had hydrocephaly+shunt, 1 had metabolic disease (propionic acidemia), 2 had a history of trauma (struck by a motor vehicle), and in 1 there was no comorbidity. Mortality developed in 6 of the 7 patients in ICU. Conclusion: In a significant proportion of children, COVID-19 has an asymptomatic course, which contributes greatly to the spread of the disease. While COVID-19 can cause morbidities such as convulsions in the paediatric population, it may also result in mortality in children with underlying serious diseases. © 2021 by Author/s and Licensed by Modestum.